STRINGSTRING
PA1851 PA1851 PA3825 PA3825 PA3258 PA3258 rocR rocR PA2567 PA2567 PA1433 PA1433 PA4396 PA4396 arr arr PA2133 PA2133 PA4781 PA4781 fimX fimX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA1851Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (401 aa)    
Predicted Functional Partners:
PA3825
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 
 0.922
PA3258
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 
 0.892
rocR
RocR; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.880
PA2567
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 0.876
PA1433
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 
 0.829
PA4396
Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
      
 0.810
arr
Aminoglycoside response regulator; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 
 0.808
PA2133
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
 
 
 0.806
PA4781
Cyclic di-GMP phosphodiesterase; Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic diguanylate (c-di-GMP) to GMP. Hydrolyzes c-di-GMP to GMP in a two-step reaction, via the linear intermediate 5'-phosphoguanylyl(3'->5')guanosine (pGpG). In vitro, can use pGpG as an alternative substrate and hydrolyze it into GMP. Acts in regulation of motility, synthesis of virulence determinants and biofilm architecture. May act preferentially as a pGpG binding protein.
  
 0.790
fimX
FimX; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.785
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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