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bdhA bdhA dhcB dhcB dhcA dhcA liuE liuE PA1997 PA1997 PA1018 PA1018 PA2004 PA2004 nuoD nuoD gcdH gcdH PA2005 PA2005 mmsB mmsB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bdhA3-hydroxybutyrate dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)    
Predicted Functional Partners:
dhcB
DhcB, dehydrocarnitine CoA transferase, subunit B; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.971
dhcA
DhcA, dehydrocarnitine CoA transferase, subunit A; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.965
liuE
3-hydroxy-3-methylglutaryl-CoA lyase; Involved in the L-leucine, isovalerate and acyclic monoterpene catabolism. Catalyzes the cleavage of 3-hydroxy-3- methylglutaryl-CoA (HMG-CoA) to yield acetyl-CoA and acetoacetate. It can also catalyze the cleavage of 3-hydroxy-3-isohexenylglutaryl-CoA (HIHG_CoA) to yield 7-methyl-3-oxooct-6-enoyl-CoA and acetate.
   
 
 0.925
PA1997
Probable AMP-binding enzyme; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 0.911
PA1018
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 0.907
PA2004
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.863
nuoD
NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.792
gcdH
glutaryl-CoA dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein).
   
 0.740
PA2005
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
     
 0.728
mmsB
3-hydroxyisobutyrate dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.655
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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