STRINGSTRING
cynT cynT cynS cynS PA0103 PA0103 PA4676 PA4676 PA0102 PA0102 cynR cynR sstT sstT PA5312 PA5312 PA1340 PA1340 PA1341 PA1341 PA2777 PA2777
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cynTCarbonate dehydratase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the beta-class carbonic anhydrase family. (220 aa)    
Predicted Functional Partners:
cynS
Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
 
 
 0.997
PA0103
Probable sulfate transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 0.956
PA4676
Probable carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
  
0.941
PA0102
Probable carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
  
0.908
cynR
Transcriptional regulator CynR; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the LysR transcriptional regulatory family.
     
 0.855
sstT
Probable transporter (membrane subunit); Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
   
  
 0.734
PA5312
Probable aldehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aldehyde dehydrogenase family.
  
  
 0.707
PA1340
Amino acid ABC transporter membrane protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
      
 0.699
PA1341
Amino acid ABC transporter membrane protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
      
 0.699
PA2777
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.638
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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