STRINGSTRING
arsC arsC arsR arsR PA2280 PA2280 arsB arsB PA3233 PA3233 PA0950 PA0950 sfsA sfsA PA3664 PA3664 pslA pslA pyrF pyrF PA4061 PA4061
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arsCArsC protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (156 aa)    
Predicted Functional Partners:
arsR
ArsR protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.989
PA2280
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.981
arsB
ArsB protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.
 
  
 0.978
PA3233
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
     
 0.891
PA0950
Probable arsenate reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.730
sfsA
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the SfsA family.
      
 0.699
PA3664
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the ArsC family.
  
  
 0.673
pslA
PslA; Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.543
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
      0.527
PA4061
Probable thioredoxin; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 
 0.526
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.