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PA2280 PA2280 arsC arsC arsR arsR arsB arsB PA4975 PA4975 PA1204 PA1204 PA1225 PA1225 PA1224 PA1224 PA0950 PA0950 wrbA wrbA PA2580 PA2580
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA2280Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (230 aa)    
Predicted Functional Partners:
arsC
ArsC protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.981
arsR
ArsR protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.945
arsB
ArsB protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.
 
  
 0.912
PA4975
NAD(P)H quinone oxidoreductase; Product name confidence: Class 2 (High similarity to functionally studied protein).
     
 0.885
PA1204
Conserved hypothetical protein; Has NAD(P)H-dependent FMN reductase activity.
      
 0.880
PA1225
Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.809
PA1224
Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
     
 0.778
PA0950
Probable arsenate reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.724
wrbA
Trp repressor binding protein WrbA; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the WrbA family.
     
 0.610
PA2580
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.607
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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