STRINGSTRING
PA2321 PA2321 edd edd pgl pgl PA2265 PA2265 gnuT gnuT PA2263 PA2263 PA2264 PA2264 PA3896 PA3896 PA2261 PA2261 gntR gntR mtlR mtlR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA2321Gluconokinase; Product name confidence: Class 2 (High similarity to functionally studied protein). (173 aa)    
Predicted Functional Partners:
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
 
 0.987
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.973
PA2265
Gluconate dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein).
   
 
 0.948
gnuT
Gluconate permease; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the GntP permease family.
 
  
 0.938
PA2263
Probable 2-hydroxyacid dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.911
PA2264
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
 
 0.907
PA3896
Probable 2-hydroxyacid dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.905
PA2261
Probable 2-ketogluconate kinase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.901
gntR
Transcriptional regulator GntR; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.875
mtlR
Transcriptional regulator MtlR; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
   
 0.850
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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