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mtlY mtlY mtlD mtlD rpe rpe tal tal mtlZ mtlZ PA2340 PA2340 PA2339 PA2339 PA2341 PA2341 PA2338 PA2338 tsaC tsaC ldhA ldhA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtlYXylulose kinase; Product name confidence: Class 2 (High similarity to functionally studied protein). (502 aa)    
Predicted Functional Partners:
mtlD
Mannitol dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the mannitol dehydrogenase family.
 
 
 0.959
rpe
Ribulose-phosphate 3-epimerase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the ribulose-phosphate 3-epimerase family.
 
  
 0.931
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.869
mtlZ
Fructokinase; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.830
PA2340
Probable binding-protein-dependent maltose/mannitol transport protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.822
PA2339
Probable binding-protein-dependent maltose/mannitol transport protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.793
PA2341
Probable ATP-binding component of ABC maltose/mannitol transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the ABC transporter superfamily.
 
  
 0.782
PA2338
Probable binding protein component of ABC maltose/mannitol transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.744
tsaC
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
      
 0.699
ldhA
D-lactate dehydrogenase (fermentative); Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.660
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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