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msuE msuE msuD msuD PA2600 PA2600 ssuD ssuD PA3954 PA3954 ssuB2 ssuB2 PA2598 PA2598 PA2355 PA2355 cysI cysI cysH cysH PA3446 PA3446
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msuENADH-dependent FMN reductase MsuE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (186 aa)    
Predicted Functional Partners:
msuD
Methanesulfonate sulfonatase MsuD; Catalyzes the desulfonation of aliphatic sulfonates. Shows highest activity with methanesulfonate; Belongs to the SsuD family.
 
 0.999
PA2600
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 0.993
ssuD
Conserved hypothetical protein; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.
 
 0.989
PA3954
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 0.981
ssuB2
Probable ATP-binding component of ABC transporter; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.
  
 
 0.970
PA2598
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
 0.964
PA2355
Probable FMNH2-dependent monooxygenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.954
cysI
Sulfite reductase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
     
 0.942
cysH
3'-phosphoadenosine-5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily.
   
 
 0.930
PA3446
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
 
 
0.927
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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