STRINGSTRING
pvdF pvdF pvdA pvdA pvdE pvdE pvdD pvdD pvdJ pvdJ purL purL fpvA fpvA pvdH pvdH pvdL pvdL pvdP pvdP pvdQ pvdQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
pvdFPyoverdine synthetase F; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (275 aa)    
Predicted Functional Partners:
pvdA
L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate.
 
 
 0.993
pvdE
Pyoverdine biosynthesis protein PvdE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.990
pvdD
Pyoverdine synthetase D; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
 
 0.984
pvdJ
PvdJ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.982
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.962
fpvA
Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine.
  
  
 0.956
pvdH
L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
  
 0.918
pvdL
PvdL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.881
pvdP
PvdP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.876
pvdQ
3-oxo-C12-homoserine lactone acylase PvdQ; Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length). Degrades 3-oxo- C12-HSL, one of the two main AHL signal molecules of P.aeruginosa, and thereby functions as a quorum quencher, inhibiting the las quorum- sensing system. Therefore, may enable P.aeruginosa to modulate its own quorum-sensing-dependent pathogenic potential. Also appears to be requ [...]
  
  
 0.875
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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