node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fpvA | pvdA | PA2398 | PA2386 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | 0.972 |
fpvA | pvdD | PA2398 | PA2399 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | Pyoverdine synthetase D; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.889 |
fpvA | pvdE | PA2398 | PA2397 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | Pyoverdine biosynthesis protein PvdE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.976 |
fpvA | pvdF | PA2398 | PA2396 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | Pyoverdine synthetase F; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.956 |
fpvA | pvdH | PA2398 | PA2413 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.809 |
fpvA | pvdJ | PA2398 | PA2400 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | PvdJ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.856 |
fpvA | pvdL | PA2398 | PA2424 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | PvdL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.703 |
fpvA | pvdP | PA2398 | PA2392 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | PvdP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.603 |
fpvA | pvdQ | PA2398 | PA2385 | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | 3-oxo-C12-homoserine lactone acylase PvdQ; Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length). Degrades 3-oxo- C12-HSL, one of the two main AHL signal molecules of P.aeruginosa, and thereby functions as a quorum quencher, inhibiting the las quorum- sensing system. Therefore, may enable P.aeruginosa to modulate its own quorum-sensing-dependent pathogenic potential. Also appears to be requ [...] | 0.670 |
purL | pvdF | PA3763 | PA2396 | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | Pyoverdine synthetase F; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.962 |
pvdA | fpvA | PA2386 | PA2398 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | 0.972 |
pvdA | pvdD | PA2386 | PA2399 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | Pyoverdine synthetase D; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.992 |
pvdA | pvdE | PA2386 | PA2397 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | Pyoverdine biosynthesis protein PvdE; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.984 |
pvdA | pvdF | PA2386 | PA2396 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | Pyoverdine synthetase F; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.993 |
pvdA | pvdH | PA2386 | PA2413 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase, PvdH; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.986 |
pvdA | pvdJ | PA2386 | PA2400 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | PvdJ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.996 |
pvdA | pvdL | PA2386 | PA2424 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | PvdL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.991 |
pvdA | pvdP | PA2386 | PA2392 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | PvdP; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.894 |
pvdA | pvdQ | PA2386 | PA2385 | L-ornithine N5-oxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as pyoverdin. Pyoverdin is a hydroxamate siderophore composed of a 6,7-dihydroxyquinoline-containing fluorescent chromophore joined to the N-terminus of a partly cyclic octapeptide (D-Ser-L-Arg-D-Ser-L-N(5)-OH-Orn-L-Lys-L-N(5)-OH-Orn-L-Thr- L-Thr in strain PAO1). Specific for NADPH, which plays a role in stabilization of the C4a-hydroperoxyflavin intermediate. | 3-oxo-C12-homoserine lactone acylase PvdQ; Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of 11 to 14 carbons in length). Degrades 3-oxo- C12-HSL, one of the two main AHL signal molecules of P.aeruginosa, and thereby functions as a quorum quencher, inhibiting the las quorum- sensing system. Therefore, may enable P.aeruginosa to modulate its own quorum-sensing-dependent pathogenic potential. Also appears to be requ [...] | 0.992 |
pvdD | fpvA | PA2399 | PA2398 | Pyoverdine synthetase D; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine. | 0.889 |