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foxA foxA foxR foxR pfeA pfeA tonB1 tonB1 foxI foxI PA0471 PA0471 fpvB fpvB PA2465 PA2465 PA0472 PA0472 fpvR fpvR femR femR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
foxAFerrioxamine receptor FoxA; Class 1: Function experimentally demonstrated in P. aeruginosa. (820 aa)    
Predicted Functional Partners:
foxR
Anti-sigma factor FoxR; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.975
pfeA
Ferric enterobactin receptor, outer membrane protein PfeA precursor; Specific receptor for the siderophore ferric enterobactin.
  
  
 0.945
tonB1
TonB1; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
 
 
 0.941
foxI
ECF sigma factor FoxI; Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the sigma-70 factor family. ECF subfamily.
 
  
 0.870
PA0471
Probable transmembrane sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.774
fpvB
Second ferric pyoverdine receptor FpvB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
0.732
PA2465
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.708
PA0472
Probable sigma-70 factor, ECF subfamily; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the sigma-70 factor family. ECF subfamily.
 
  
 0.675
fpvR
FpvR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.655
femR
Sigma factor regulator, FemR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.649
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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