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PA2555 PA2555 PA2553 PA2553 PA2552 PA2552 pta pta prpC prpC PA2554 PA2554 ackA ackA atoB atoB gltA gltA glcB glcB PA3589 PA3589
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA2555Probable AMP-binding enzyme; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (555 aa)    
Predicted Functional Partners:
PA2553
Probable acyl-CoA thiolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.993
PA2552
Probable acyl-CoA dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 
 0.991
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
  
 
 0.970
prpC
Citrate synthase 2; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the citrate synthase family.
  
 0.962
PA2554
Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.962
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.961
atoB
acetyl-CoA acetyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.958
gltA
Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 0.955
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.953
PA3589
Probable acyl-CoA thiolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.945
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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