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pgsA pgsA pgpA pgpA pssA pssA cdsA cdsA PA2536 PA2536 pcs pcs uvrC uvrC PA2541 PA2541 cls cls psd psd PA3618 PA3618
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgsACDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (186 aa)    
Predicted Functional Partners:
pgpA
Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
 
 
 0.987
pssA
Phosphatidylserine synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.979
cdsA
Phosphatidate cytidylyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.964
PA2536
Probable phosphatidate cytidylyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
  0.958
pcs
Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.925
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
  
  
 0.916
PA2541
Probable CDP-alcohol phosphatidyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
    
  0.902
cls
Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
 
   
 0.870
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
 
 
 
 0.844
PA3618
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the CinA family.
 
  
 0.795
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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