STRINGSTRING
pelF pelF pelG pelG pelD pelD pelE pelE pelC pelC pelA pelA pelB pelB pslA pslA pslD pslD algD algD alg8 alg8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pelFPelF; Class 1: Function experimentally demonstrated in P. aeruginosa. (507 aa)    
Predicted Functional Partners:
pelG
PelG; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.997
pelD
PelD; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.997
pelE
PelE; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.995
pelC
PelC; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.994
pelA
PelA; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.992
pelB
PelB; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.987
pslA
PslA; Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.903
pslD
PslD; Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.903
algD
GDP-mannose 6-dehydrogenase AlgD; Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics.
  
  
 0.721
alg8
Alginate biosynthesis protein Alg8; Processive enzyme that polymerizes GDP-mannuronic acid. Belongs to the glycosyltransferase 2 family.
  
  
 0.707
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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