STRINGSTRING
pelC pelC pelD pelD pelG pelG pelF pelF pelE pelE pelB pelB pelA pelA ndvB ndvB algC algC wspF wspF alg8 alg8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pelCPelC; Class 1: Function experimentally demonstrated in P. aeruginosa. (172 aa)    
Predicted Functional Partners:
pelD
PelD; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.997
pelG
PelG; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.994
pelF
PelF; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.994
pelE
PelE; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.994
pelB
PelB; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.992
pelA
PelA; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.987
ndvB
NdvB; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
   
  
 0.771
algC
Phosphomannomutase AlgC; Highly reversible phosphoryltransferase. The phosphomannomutase activity produces a precursor for alginate polymerization, the alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core lipopolysaccaride (LPS) biosynthesis due to its phosphoglucomutase activity. Essential for rhamnolipid production, an exoproduct correlated with pathogenicity. Required for biofilm production. The reaction proceeds via 2 processive phosphoryl transferase reactions; first from enzyme-phospho-Ser-1 [...]
      
 0.497
wspF
Probable methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
      
 0.414
alg8
Alginate biosynthesis protein Alg8; Processive enzyme that polymerizes GDP-mannuronic acid. Belongs to the glycosyltransferase 2 family.
  
   
 0.401
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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