node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fimV | truA | PA3115 | PA3114 | Motility protein FimV; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | tRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.872 |
miaA | micA | PA4945 | PA0382 | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.750 |
miaA | rluA | PA4945 | PA3246 | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Pseudouridine synthase RluA; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.480 |
miaA | rpoA | PA4945 | PA4238 | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.559 |
miaA | thiI | PA4945 | PA5118 | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Thiazole biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.713 |
miaA | tilS | PA4945 | PA3638 | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.571 |
miaA | truA | PA4945 | PA3114 | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | tRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.917 |
miaA | truB | PA4945 | PA4742 | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity). Osmoprotectant regulator of PLC; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.873 |
micA | miaA | PA0382 | PA4945 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.750 |
micA | rluA | PA0382 | PA3246 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Pseudouridine synthase RluA; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.861 |
micA | rsuA | PA0382 | PA0733 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Probable pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.415 |
micA | thiI | PA0382 | PA5118 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Thiazole biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.824 |
micA | tilS | PA0382 | PA3638 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.697 |
micA | truA | PA0382 | PA3114 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | tRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.938 |
micA | truB | PA0382 | PA4742 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (By similarity). Osmoprotectant regulator of PLC; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.962 |
micA | truD | PA0382 | PA3626 | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.765 |
rluA | miaA | PA3246 | PA4945 | Pseudouridine synthase RluA; Product name confidence: Class 2 (High similarity to functionally studied protein). | Delta 2-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.480 |
rluA | micA | PA3246 | PA0382 | Pseudouridine synthase RluA; Product name confidence: Class 2 (High similarity to functionally studied protein). | DNA mismatch repair protein MicA; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.861 |
rluA | rsuA | PA3246 | PA0733 | Pseudouridine synthase RluA; Product name confidence: Class 2 (High similarity to functionally studied protein). | Probable pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.924 |
rluA | thiI | PA3246 | PA5118 | Pseudouridine synthase RluA; Product name confidence: Class 2 (High similarity to functionally studied protein). | Thiazole biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.671 |