node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0223 | dapA | PA0223 | PA1010 | Probable dihydrodipicolinate synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the DapA family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | 0.951 |
PA0223 | hom | PA0223 | PA3736 | Probable dihydrodipicolinate synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the DapA family. | Homoserine dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.919 |
PA0223 | lysC | PA0223 | PA0904 | Probable dihydrodipicolinate synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the DapA family. | Aspartate kinase alpha and beta chain; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the aspartokinase family. | 0.481 |
PA0223 | usg | PA0223 | PA3116 | Probable dihydrodipicolinate synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the DapA family. | Probable aspartate-semialdehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.739 |
PA1254 | usg | PA1254 | PA3116 | Probable dihydrodipicolinate synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the DapA family. | Probable aspartate-semialdehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.727 |
PA3018 | usg | PA3018 | PA3116 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable aspartate-semialdehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.885 |
dapA | PA0223 | PA1010 | PA0223 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | Probable dihydrodipicolinate synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the DapA family. | 0.951 |
dapA | dapF | PA1010 | PA5278 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.930 |
dapA | hom | PA1010 | PA3736 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | Homoserine dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.953 |
dapA | lysC | PA1010 | PA0904 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | Aspartate kinase alpha and beta chain; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the aspartokinase family. | 0.820 |
dapA | truA | PA1010 | PA3114 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | tRNA-pseudouridine synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.417 |
dapA | usg | PA1010 | PA3116 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | Probable aspartate-semialdehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.910 |
dapF | dapA | PA5278 | PA1010 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | 0.930 |
dapF | leuB | PA5278 | PA3118 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.521 |
dapF | lysC | PA5278 | PA0904 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartate kinase alpha and beta chain; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the aspartokinase family. | 0.592 |
dapF | usg | PA5278 | PA3116 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Probable aspartate-semialdehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.707 |
hom | PA0223 | PA3736 | PA0223 | Homoserine dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Probable dihydrodipicolinate synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the DapA family. | 0.919 |
hom | dapA | PA3736 | PA1010 | Homoserine dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family. | 0.953 |
hom | leuB | PA3736 | PA3118 | Homoserine dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.533 |
hom | lysC | PA3736 | PA0904 | Homoserine dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Aspartate kinase alpha and beta chain; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the aspartokinase family. | 0.929 |