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PA3127 PA3127 PA5249 PA5249 PA5248 PA5248 PA3128 PA3128 vgrG5 vgrG5 wapR wapR fiuA fiuA ibpA ibpA nuoD nuoD wbpM wbpM murB murB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA3127Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (267 aa)    
Predicted Functional Partners:
PA5249
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.883
PA5248
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.881
PA3128
Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 
 0.772
vgrG5
Conserved hypothetical protein; Part of the H2 type VI secretion system (H2-T6SS) specialized secretion system, which delivers several virulence factors in both prokaryotic and eukaryotic cells during infection. Allows the delivery of the phospholipase effector PldB to target cells where it exerts its toxicity. Plays also a role in VgrG4b and its effector PldA secretion.
      
 0.698
wapR
Alpha-1,3-rhamnosyltransferase WapR; Class 1: Function experimentally demonstrated in P. aeruginosa.
   
  
 0.606
fiuA
Ferrichrome receptor FiuA; Class 1: Function experimentally demonstrated in P. aeruginosa.
      
 0.586
ibpA
Heat-shock protein IbpA; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the small heat shock protein (HSP20) family.
  
  
 0.545
nuoD
NADH dehydrogenase I chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
  
 0.506
wbpM
Nucleotide sugar epimerase/dehydratase WbpM; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.501
murB
UDP-N-acetylpyruvoylglucosamine reductase; Cell wall formation.
     
 0.499
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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