STRINGSTRING
oprO oprO PA3383 PA3383 oprB oprB oprD oprD oprF oprF phnC phnC phoA phoA PA2635 PA2635 PA2804 PA2804 PA1974 PA1974 oprE oprE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
oprOPyrophosphate-specific outer membrane porin OprO precursor; Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate; Belongs to the OprO/OprP family. (438 aa)    
Predicted Functional Partners:
PA3383
Binding protein component of ABC phosphonate transporter; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.915
oprB
Glucose/carbohydrate outer membrane porin OprB precursor; Substrate-selective channel for a variety of different sugars. Could potentially facilitate the diffusion of diverse compounds, dependent on the presence of a hydroxyl group, but is presumably restricted to carbohydrates. Involved in the transport of glucose, mannitol, fructose and glycerol (sugars able to support the growth of P.aeruginosa). Facilitates glucose diffusion across the outer membrane.
     
 0.904
oprD
Basic amino acid, basic peptide and imipenem outer membrane porin OprD precursor; Porin with a specificity for basic amino acids. Also possesses serine protease activity; Belongs to the outer membrane porin (Opr) (TC 1.B.25) family.
  
  
 0.898
oprF
Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
  
 0.834
phnC
ATP-binding component of ABC phosphonate transporter; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
   
  
 0.810
phoA
Alkaline phosphatase; Has only phosphomonoesterase activity. Belongs to the alkaline phosphatase family.
   
  
 0.790
PA2635
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
    0.782
PA2804
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
    0.772
PA1974
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
    0.768
oprE
Anaerobically-induced outer membrane porin OprE precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
   
 0.753
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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