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PA3415 PA3415 PA3416 PA3416 pdhA pdhA lpdV lpdV lpd3 lpd3 lpdG lpdG PA4152 PA4152 aceE aceE bkdA2 bkdA2 bkdA1 bkdA1 pta pta
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
PA3415Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (370 aa)    
Predicted Functional Partners:
PA3416
Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 0.999
pdhA
Probable pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.999
lpdV
Lipoamide dehydrogenase-Val; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 0.991
lpd3
Dihydrolipoamide dehydrogenase 3; LPD-3 may substitute for lipoamide dehydrogenase of the 2- oxoglutarate dehydrogenase and pyruvate multienzyme complexes when the latter is inactive or missing; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 0.987
lpdG
Lipoamide dehydrogenase-glc; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
 0.986
PA4152
Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 0.981
aceE
Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.980
bkdA2
2-oxoisovalerate dehydrogenase (beta subunit); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
 
 0.976
bkdA1
2-oxoisovalerate dehydrogenase (alpha subunit); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity); Belongs to the BCKDHA family.
 
 0.964
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
  
 
 0.957
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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