node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA3415 | PA3416 | PA3415 | PA3416 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.999 |
PA3415 | PA4152 | PA3415 | PA4152 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.981 |
PA3415 | aceE | PA3415 | PA5015 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.980 |
PA3415 | bkdA1 | PA3415 | PA2247 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 2-oxoisovalerate dehydrogenase (alpha subunit); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity); Belongs to the BCKDHA family. | 0.964 |
PA3415 | bkdA2 | PA3415 | PA2248 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 2-oxoisovalerate dehydrogenase (beta subunit); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.976 |
PA3415 | lpd3 | PA3415 | PA4829 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Dihydrolipoamide dehydrogenase 3; LPD-3 may substitute for lipoamide dehydrogenase of the 2- oxoglutarate dehydrogenase and pyruvate multienzyme complexes when the latter is inactive or missing; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.987 |
PA3415 | lpdG | PA3415 | PA1587 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Lipoamide dehydrogenase-glc; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.986 |
PA3415 | lpdV | PA3415 | PA2250 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Lipoamide dehydrogenase-Val; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.991 |
PA3415 | pdhA | PA3415 | PA3417 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
PA3415 | pta | PA3415 | PA0835 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Phosphate acetyltransferase; Involved in acetate metabolism. In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. | 0.957 |
PA3416 | PA3415 | PA3416 | PA3415 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.999 |
PA3416 | PA4152 | PA3416 | PA4152 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.983 |
PA3416 | aceE | PA3416 | PA5015 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.910 |
PA3416 | bkdA1 | PA3416 | PA2247 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 2-oxoisovalerate dehydrogenase (alpha subunit); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity); Belongs to the BCKDHA family. | 0.996 |
PA3416 | lpd3 | PA3416 | PA4829 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Dihydrolipoamide dehydrogenase 3; LPD-3 may substitute for lipoamide dehydrogenase of the 2- oxoglutarate dehydrogenase and pyruvate multienzyme complexes when the latter is inactive or missing; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.990 |
PA3416 | lpdG | PA3416 | PA1587 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Lipoamide dehydrogenase-glc; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.983 |
PA3416 | lpdV | PA3416 | PA2250 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Lipoamide dehydrogenase-Val; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.991 |
PA3416 | pdhA | PA3416 | PA3417 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
PA3416 | pta | PA3416 | PA0835 | Probable pyruvate dehydrogenase E1 component, beta chain; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Phosphate acetyltransferase; Involved in acetate metabolism. In combination with LdhA and AckA, allows fermentation of pyruvate, enhancing long-term survival under anaerobic conditions; In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family. | 0.783 |
PA4152 | PA3415 | PA4152 | PA3415 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.981 |