STRINGSTRING
folX folX folE1 folE1 folM folM folE2 folE2 wrbA wrbA eddA eddA folE2-2 folE2-2 PA2666 PA2666 phoA phoA folP folP PA0583 PA0583
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folXD-erythro-7,8-dihydroneopterin triphosphate epimerase; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. (123 aa)    
Predicted Functional Partners:
folE1
GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.995
folM
Dihydromonapterin reductase, FolM; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.987
folE2
GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.968
wrbA
Trp repressor binding protein WrbA; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the WrbA family.
     
 0.931
eddA
Extracelullar DNA degradation protein, EddA; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.930
folE2-2
Hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
 
  
 0.923
PA2666
Probable 6-pyruvoyl tetrahydrobiopterin synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 
 0.920
phoA
Alkaline phosphatase; Has only phosphomonoesterase activity. Belongs to the alkaline phosphatase family.
     
  0.900
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.879
PA0583
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.797
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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