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fruK fruK fruA fruA fruI fruI fda fda fbp fbp ptsN ptsN PA3760 PA3760 PA1490 PA1490 glpR glpR glmR glmR fruR fruR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruK1-phosphofructokinase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the carbohydrate kinase PfkB family. (314 aa)    
Predicted Functional Partners:
fruA
Phosphotransferase system transporter fructose-specific IIBC component, FruA; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.999
fruI
Phosphotransferase system transporter enzyme I, FruI; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the PEP-utilizing enzyme family.
 
  
 0.999
fda
Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.961
fbp
Fructose-1,6-bisphosphatase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.946
ptsN
Nitrogen regulatory IIA protein; Seems to have a role in regulating nitrogen assimilation.
 
  
 0.942
PA3760
N-Acetyl-D-Glucosamine phosphotransferase system transporter; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.898
PA1490
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.893
glpR
Glycerol-3-phosphate regulon repressor; Repressor of the glycerol-3-phosphate regulon.
 
  
 0.867
glmR
GlmR transcriptional regulator; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.855
fruR
Fructose transport system repressor FruR; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.841
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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