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fruR fruR fruA fruA fruI fruI PA3760 PA3760 gltB gltB fruK fruK gntR gntR PA3327 PA3327 fbp fbp mtlZ mtlZ PA2261 PA2261
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruRFructose transport system repressor FruR; Product name confidence: Class 2 (High similarity to functionally studied protein). (329 aa)    
Predicted Functional Partners:
fruA
Phosphotransferase system transporter fructose-specific IIBC component, FruA; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.968
fruI
Phosphotransferase system transporter enzyme I, FruI; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the PEP-utilizing enzyme family.
 
 
 0.946
PA3760
N-Acetyl-D-Glucosamine phosphotransferase system transporter; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.903
gltB
Glutamate synthase large chain precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 
 0.856
fruK
1-phosphofructokinase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.841
gntR
Transcriptional regulator GntR; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.783
PA3327
Probable non-ribosomal peptide synthetase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
    
 
 0.718
fbp
Fructose-1,6-bisphosphatase; Product name confidence: Class 2 (High similarity to functionally studied protein).
   
  
 0.713
mtlZ
Fructokinase; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.664
PA2261
Probable 2-ketogluconate kinase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.654
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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