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glpK1 glpK1 glpD glpD PA3025 PA3025 glpK glpK glpF glpF plsY plsY plsB plsB PA1487 PA1487 PA2275 PA2275 PA3580 PA3580 PA3023 PA3023
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Experiments
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[Homology]
Score
glpK1Probable carbohydrate kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (494 aa)    
Predicted Functional Partners:
glpD
Glycerol-3-phosphate dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 0.991
PA3025
Probable FAD-dependent glycerol-3-phosphate dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 0.972
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
 
0.957
glpF
Glycerol uptake facilitator protein; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane.
 
 
 0.940
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.926
plsB
Glycerol-3-phosphate acyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the GPAT/DAPAT family.
     
 0.922
PA1487
Probable carbohydrate kinase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the FGGY kinase family.
  
  
0.918
PA2275
Probable alcohol dehydrogenase (Zn-dependent); Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
    
 0.909
PA3580
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
  
  
 0.799
PA3023
Conserved hypothetical protein; Probably phosphorylates lipids; the in vivo substrate is unknown.
      
 0.784
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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