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dgkA dgkA cdsA cdsA lptA lptA plcN plcN plcH plcH PA2536 PA2536 lipA lipA lipC lipC gpsA gpsA ybeY ybeY PA2927 PA2927
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
dgkADiacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (123 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.924
lptA
Lysophosphatidic acid acyltransferase, LptA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.906
plcN
Non-hemolytic phospholipase C precursor; Hydrolyzes phosphatidylserine as well as phosphatidylcholine.
   
 
  0.901
plcH
Hemolytic phospholipase C precursor; Hydrolyzes sphingomyelin in addition to phosphatidylcholine.
     
  0.900
PA2536
Probable phosphatidate cytidylyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
     
  0.900
lipA
Lactonizing lipase precursor; Catalyzes the hydrolysis of triacylglycerol. It also exhibits some esterase activity with p-nitrophenyl acetate and Tween 80 as substrates, however the lipase activity is approximately eight times the esterase activity. It shows a marked specificity for the 1,3-oleyl residues of triolein.
     
 0.900
lipC
Lipase LipC; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
     
 0.900
gpsA
Glycerol-3-phosphate dehydrogenase, biosynthetic; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.877
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.868
PA2927
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.822
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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