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PA3628 PA3628 adhC adhC fdhA fdhA fdnG fdnG fdnI fdnI fdnH fdnH PA3631 PA3631 purU2 purU2 soxG soxG PA0475 PA0475 PA3749 PA3749
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA3628Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde. (283 aa)    
Predicted Functional Partners:
adhC
Alcohol dehydrogenase class III; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.999
fdhA
Glutathione-independent formaldehyde dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formaldehyde and acetoaldehyde; Belongs to the zinc-containing alcohol dehydrogenase family.
  
 
 0.951
fdnG
Formate dehydrogenase-O, major subunit; Product name confidence: Class 2: Function of highly similar gene experimentally demonstrated in another organism (and gene context consistent in terms of pathways its involved in, if known).
  
 
  0.911
fdnI
Nitrate-inducible formate dehydrogenase, gamma subunit; Product name confidence: Class 2 (High similarity to functionally studied protein).
     
  0.900
fdnH
Nitrate-inducible formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
   
 
  0.900
PA3631
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.839
purU2
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
  
  
 0.814
soxG
Sarcosine oxidase gamma subunit; Class 1: Function experimentally demonstrated in P. aeruginosa.
   
    0.766
PA0475
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
      
 0.759
PA3749
Probable major facilitator superfamily (MFS) transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
      
 0.759
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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