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plsB plsB plsY plsY plsX plsX gpsA gpsA glpD glpD PA3025 PA3025 lptA lptA PA1487 PA1487 glpK1 glpK1 glpK glpK fabA fabA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
plsBGlycerol-3-phosphate acyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the GPAT/DAPAT family. (834 aa)    
Predicted Functional Partners:
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
     
 0.991
plsX
Fatty acid biosynthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
   
 
 0.991
gpsA
Glycerol-3-phosphate dehydrogenase, biosynthetic; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 
 0.962
glpD
Glycerol-3-phosphate dehydrogenase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
    
 0.961
PA3025
Probable FAD-dependent glycerol-3-phosphate dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
    
 0.944
lptA
Lysophosphatidic acid acyltransferase, LptA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.926
PA1487
Probable carbohydrate kinase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the FGGY kinase family.
     
 0.922
glpK1
Probable carbohydrate kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
     
 0.922
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
     
 0.922
fabA
beta-hydroxydecanoyl-ACP dehydrase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity).
   
  
 0.816
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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