node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA3576 | PA5130 | PA3576 | PA5130 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.883 |
PA3576 | armR | PA3576 | PA3719 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.767 |
PA3677 | armR | PA3677 | PA3719 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.563 |
PA3677 | mexB | PA3677 | PA0426 | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB; The inner membrane transporter component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Implicated in the secretion of the siderophore pyoverdine; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.544 |
PA3720 | armR | PA3720 | PA3719 | Hypothetical protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.993 |
PA3720 | mexA | PA3720 | PA0425 | Hypothetical protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor; The periplasmic linker component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Required for assembly of the MexA/MexB/OprM complex. Implicated in the secretion of the siderophore pyoverdine; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.691 |
PA3720 | mexR | PA3720 | PA0424 | Hypothetical protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Multidrug resistance operon repressor MexR; Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon. | 0.882 |
PA3720 | nalC | PA3720 | PA3721 | Hypothetical protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | NalC; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.984 |
PA3720 | nalD | PA3720 | PA3574 | Hypothetical protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | NalD; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.824 |
PA3720 | oprM | PA3720 | PA0427 | Hypothetical protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Major intrinsic multiple antibiotic resistance efflux outer membrane protein OprM precursor; The outer membrane component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Can replace the OprJ outer membrane component of the MexCD-OprJ pump; the antibiotics exported are those exported by the intact MexCD pump, showing that efflux substrate specificity is not conferred by this component. Serves as the outer membrane co [...] | 0.768 |
PA5130 | PA3576 | PA5130 | PA3576 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.883 |
PA5130 | armR | PA5130 | PA3719 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.767 |
armR | PA3576 | PA3719 | PA3576 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.767 |
armR | PA3677 | PA3719 | PA3677 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.563 |
armR | PA3720 | PA3719 | PA3720 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Hypothetical protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.993 |
armR | PA5130 | PA3719 | PA5130 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.767 |
armR | mexA | PA3719 | PA0425 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor; The periplasmic linker component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Required for assembly of the MexA/MexB/OprM complex. Implicated in the secretion of the siderophore pyoverdine; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.700 |
armR | mexB | PA3719 | PA0426 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB; The inner membrane transporter component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Implicated in the secretion of the siderophore pyoverdine; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.568 |
armR | mexR | PA3719 | PA0424 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | Multidrug resistance operon repressor MexR; Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon. | 0.999 |
armR | nalC | PA3719 | PA3721 | Antirepressor for MexR, ArmR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | NalC; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.965 |