node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purB | purC | PA2629 | PA1013 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | 0.989 |
purB | purD | PA2629 | PA4855 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylamine--glycine ligase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.934 |
purB | purE | PA2629 | PA5426 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.848 |
purB | purF | PA2629 | PA3108 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.923 |
purB | purH | PA2629 | PA4854 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.997 |
purB | purK | PA2629 | PA5425 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.911 |
purB | purL | PA2629 | PA3763 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.983 |
purB | purM | PA2629 | PA0945 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylaminoimidazole synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.985 |
purB | purN | PA2629 | PA0944 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylaminoimidazole synthetase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.908 |
purB | purT | PA2629 | PA3751 | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.554 |
purC | purB | PA1013 | PA2629 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Adenylosuccinate lyase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.989 |
purC | purD | PA1013 | PA4855 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.988 |
purC | purE | PA1013 | PA5426 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | PA1013 | PA3108 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.987 |
purC | purH | PA1013 | PA4854 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.996 |
purC | purK | PA1013 | PA5425 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. | 0.985 |
purC | purL | PA1013 | PA3763 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.999 |
purC | purM | PA1013 | PA0945 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.995 |
purC | purN | PA1013 | PA0944 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole synthetase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.969 |
purC | purT | PA1013 | PA3751 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.725 |