node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA3778 | xseA | PA3778 | PA3777 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the LysR transcriptional regulatory family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.785 |
dinG | polA | PA1045 | PA5493 | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.901 |
dinG | recJ | PA1045 | PA3725 | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | single-stranded-DNA-specific exonuclease RecJ; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.493 |
dinG | recN | PA1045 | PA4763 | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.593 |
dinG | rnhB | PA1045 | PA3642 | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.774 |
dinG | ruvA | PA1045 | PA0966 | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.564 |
dinG | xseA | PA1045 | PA3777 | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.807 |
dinG | xseB | PA1045 | PA4042 | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.538 |
ispA | polA | PA4043 | PA5493 | Geranyltranstransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the FPP/GGPP synthase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.486 |
ispA | xseA | PA4043 | PA3777 | Geranyltranstransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.791 |
ispA | xseB | PA4043 | PA4042 | Geranyltranstransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.982 |
mfd | polA | PA3002 | PA5493 | Transcription-repair coupling protein Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | 0.828 |
mfd | recJ | PA3002 | PA3725 | Transcription-repair coupling protein Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | single-stranded-DNA-specific exonuclease RecJ; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.725 |
mfd | recN | PA3002 | PA4763 | Transcription-repair coupling protein Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.722 |
mfd | ruvA | PA3002 | PA0966 | Transcription-repair coupling protein Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.611 |
mfd | xseA | PA3002 | PA3777 | Transcription-repair coupling protein Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.726 |
mfd | xseB | PA3002 | PA4042 | Transcription-repair coupling protein Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.625 |
polA | dinG | PA5493 | PA1045 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Hypothetical protein; DNA-dependent ATPase and 5'-3' DNA helicase. | 0.901 |
polA | ispA | PA5493 | PA4043 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Geranyltranstransferase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the FPP/GGPP synthase family. | 0.486 |
polA | mfd | PA5493 | PA3002 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. | Transcription-repair coupling protein Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.828 |