STRINGSTRING
oprG oprG hemN hemN ccoO2 ccoO2 oprF oprF ccoN2 ccoN2 oprH oprH PA3309 PA3309 oprE oprE ppk2 ppk2 adhA adhA ccoP2 ccoP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oprGOuter membrane protein OprG precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (232 aa)    
Predicted Functional Partners:
hemN
Oxygen-independent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.958
ccoO2
Cytochrome c oxidase, cbb3-type, CcoO subunit; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.952
oprF
Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
  
 0.944
ccoN2
Cytochrome c oxidase, cbb3-type, CcoN subunit; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the heme-copper respiratory oxidase family.
  
  
 0.933
oprH
PhoP/Q and low Mg2+ inducible outer membrane protein H1 precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.930
PA3309
Conserved hypothetical protein; Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.902
oprE
Anaerobically-induced outer membrane porin OprE precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.889
ppk2
Conserved hypothetical protein; Uses inorganic polyphosphate (polyP) as a donor to convert ADP to ATP and GDP to GTP. Can also catalyze the synthesis of polyP from ATP or GTP, but the rate of polyP utilization is 75-fold greater than the rate of polyP synthesis; Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
   
  
 0.886
adhA
Alcohol dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein).
   
  
 0.883
ccoP2
Cytochrome c oxidase, cbb3-type, CcoP subunit; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
  
 0.870
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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