node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA3440 | PA4090 | PA3440 | PA4090 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.410 |
PA4087 | PA4088 | PA4087 | PA4088 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable aminotransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.783 |
PA4087 | PA4089 | PA4087 | PA4089 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.815 |
PA4087 | PA4090 | PA4087 | PA4090 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.435 |
PA4088 | PA4087 | PA4088 | PA4087 | Probable aminotransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.783 |
PA4088 | PA4089 | PA4088 | PA4089 | Probable aminotransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.783 |
PA4088 | PA4090 | PA4088 | PA4090 | Probable aminotransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.437 |
PA4089 | PA4087 | PA4089 | PA4087 | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.815 |
PA4089 | PA4088 | PA4089 | PA4088 | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable aminotransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.783 |
PA4089 | PA4090 | PA4089 | PA4090 | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.437 |
PA4089 | hpaA | PA4089 | PA4091 | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 4-hydroxyphenylacetate 3-monooxygenase large chain; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN. In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde. | 0.447 |
PA4089 | hpaC | PA4089 | PA4092 | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 4-hydroxyphenylacetate 3-monooxygenase small chain; Reductase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the reduction of FAD by NADH. The reduced flavin is then transferred to the oxygenase component HpaB. Is also able to reduce FMN and riboflavin, but preferentially binds FAD. Has no activity with NADPH as the reductant; Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily. | 0.565 |
PA4090 | PA3440 | PA4090 | PA3440 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.410 |
PA4090 | PA4087 | PA4090 | PA4087 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.435 |
PA4090 | PA4088 | PA4090 | PA4088 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable aminotransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.437 |
PA4090 | PA4089 | PA4090 | PA4089 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.437 |
PA4090 | hpaA | PA4090 | PA4091 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 4-hydroxyphenylacetate 3-monooxygenase large chain; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN. In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde. | 0.467 |
PA4090 | hpaC | PA4090 | PA4092 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 4-hydroxyphenylacetate 3-monooxygenase small chain; Reductase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the reduction of FAD by NADH. The reduced flavin is then transferred to the oxygenase component HpaB. Is also able to reduce FMN and riboflavin, but preferentially binds FAD. Has no activity with NADPH as the reductant; Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily. | 0.415 |
PA4090 | parE | PA4090 | PA4967 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.418 |
hpaA | PA4089 | PA4091 | PA4089 | 4-hydroxyphenylacetate 3-monooxygenase large chain; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN. In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde. | Probable short-chain dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.447 |