Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PA4111 | ampC | PA4111 | PA4110 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | 0.925 |
| PA4111 | ampR | PA4111 | PA4109 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Transcriptional regulator AmpR; This protein is a positive regulator of gene expression of beta-lactamase (AmpC); Belongs to the LysR transcriptional regulatory family. | 0.639 |
| ampC | PA4111 | PA4110 | PA4111 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.925 |
| ampC | ampD | PA4110 | PA4522 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.889 |
| ampC | ampDh2 | PA4110 | PA5485 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.888 |
| ampC | ampDh3 | PA4110 | PA0807 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.887 |
| ampC | ampG | PA4110 | PA4393 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | AmpG; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.889 |
| ampC | ampR | PA4110 | PA4109 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | Transcriptional regulator AmpR; This protein is a positive regulator of gene expression of beta-lactamase (AmpC); Belongs to the LysR transcriptional regulatory family. | 0.941 |
| ampC | ftsI | PA4110 | PA4418 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin. | 0.894 |
| ampC | gyrA | PA4110 | PA3168 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.890 |
| ampC | mexB | PA4110 | PA0426 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB; The inner membrane transporter component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Implicated in the secretion of the siderophore pyoverdine; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.887 |
| ampC | nagZ | PA4110 | PA3005 | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | beta-N-acetyl-D-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides (By similarity). Contributes to intrinsic fosfomycin resistance in P.aeruginosa ; Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.903 |
| ampD | ampC | PA4522 | PA4110 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | Beta-lactamase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the class-C beta-lactamase family. | 0.889 |
| ampD | ampDh2 | PA4522 | PA5485 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | AmpDh2; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.457 |
| ampD | ampDh3 | PA4522 | PA0807 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | AmpDh3; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.486 |
| ampD | ampG | PA4522 | PA4393 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | AmpG; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.910 |
| ampD | ampR | PA4522 | PA4109 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | Transcriptional regulator AmpR; This protein is a positive regulator of gene expression of beta-lactamase (AmpC); Belongs to the LysR transcriptional regulatory family. | 0.883 |
| ampD | ftsI | PA4522 | PA4418 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin. | 0.795 |
| ampD | gyrA | PA4522 | PA3168 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.793 |
| ampD | mexB | PA4522 | PA0426 | Beta-lactamase expression regulator AmpD; Product name confidence: Class 2 (High similarity to functionally studied protein). | Resistance-Nodulation-Cell Division (RND) multidrug efflux transporter MexB; The inner membrane transporter component of the MexAB-OprM efflux system that confers multidrug resistance. Also functions as the major efflux pump for n-hexane and p-xylene efflux. Over-expression of the pump increases antibiotic and solvent efflux capacities. Implicated in the secretion of the siderophore pyoverdine; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. | 0.507 |
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