STRINGSTRING
PA4114 PA4114 speC speC aguB aguB spuC spuC PA0421 PA0421 speE speE speE2 speE2 PA0120 PA0120 ribB ribB PA0830 PA0830 PA1416 PA1416
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA4114Spermidine acetyltransferase; Product name confidence: Class 2 (High similarity to functionally studied protein). (169 aa)    
Predicted Functional Partners:
speC
Ornithine decarboxylase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
   
  0.907
aguB
N-carbamoylputrescine amidohydrolase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
    
  0.900
spuC
Putrescine aminotransferase; Involved in the putrescine catabolism. Catalyzes the transfer of the amino group from putrescine to pyruvate to yield 4-aminobutanal and alanine; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
PA0421
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
     
 0.900
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
  0.900
speE2
Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
  0.900
PA0120
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
      
 0.883
ribB
GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
  
  
 0.846
PA0830
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.768
PA1416
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.767
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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