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PA4120 PA4120 hpcB hpcB hpcD hpcD PA4122 PA4122 PA4121 PA4121 hpcG hpcG PA4128 PA4128 hpcC hpcC PA4126 PA4126 PA4135 PA4135 aph aph
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA4120Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (303 aa)    
Predicted Functional Partners:
hpcB
Homoprotocatechuate 2,3-dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.963
hpcD
5-carboxymethyl-2-hydroxymuconate isomerase; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.955
PA4122
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.933
PA4121
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
  
 0.927
hpcG
2-oxo-hept-3-ene-1,7-dioate hydratase; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
    0.912
PA4128
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the HpcH/HpaI aldolase family.
 
  
 0.906
hpcC
5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the aldehyde dehydrogenase family.
 
  
 0.901
PA4126
Probable major facilitator superfamily (MFS) transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.780
PA4135
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.714
aph
Aminoglycoside 3'-phosphotransferase type IIb; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the aminoglycoside phosphotransferase family.
  
  
 0.705
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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