node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA4120 | PA4121 | PA4120 | PA4121 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.927 |
PA4120 | PA4122 | PA4120 | PA4122 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.933 |
PA4120 | PA4126 | PA4120 | PA4126 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable major facilitator superfamily (MFS) transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.780 |
PA4120 | PA4128 | PA4120 | PA4128 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the HpcH/HpaI aldolase family. | 0.906 |
PA4120 | hpcB | PA4120 | PA4124 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Homoprotocatechuate 2,3-dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.963 |
PA4120 | hpcC | PA4120 | PA4123 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the aldehyde dehydrogenase family. | 0.901 |
PA4120 | hpcD | PA4120 | PA4125 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 5-carboxymethyl-2-hydroxymuconate isomerase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.955 |
PA4120 | hpcG | PA4120 | PA4127 | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 2-oxo-hept-3-ene-1,7-dioate hydratase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.912 |
PA4121 | PA4120 | PA4121 | PA4120 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.927 |
PA4121 | PA4122 | PA4121 | PA4122 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.997 |
PA4121 | PA4126 | PA4121 | PA4126 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable major facilitator superfamily (MFS) transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.912 |
PA4121 | PA4128 | PA4121 | PA4128 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the HpcH/HpaI aldolase family. | 0.934 |
PA4121 | hpaA | PA4121 | PA4091 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 4-hydroxyphenylacetate 3-monooxygenase large chain; Oxygenase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the hydroxylation of 4-hydroxyphenylacetate to form 3,4-dihydroxyphenylacetate, using FADH(-) provided by the reductase component HpaC to activate oxygen. To a lesser extent, can also use reduced FMN. In vitro, has hydroxylation activity toward tyrosol and various cinnamic acid derivatives, catalyzing the hydroxylation of p-coumaric acid, caffeic acid, ferulic acid, and coniferaldehyde. | 0.465 |
PA4121 | hpaC | PA4121 | PA4092 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 4-hydroxyphenylacetate 3-monooxygenase small chain; Reductase component of the 4-hydroxyphenylacetate (HPA) 3- hydroxylase. Catalyzes the reduction of FAD by NADH. The reduced flavin is then transferred to the oxygenase component HpaB. Is also able to reduce FMN and riboflavin, but preferentially binds FAD. Has no activity with NADPH as the reductant; Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily. | 0.516 |
PA4121 | hpcB | PA4121 | PA4124 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Homoprotocatechuate 2,3-dioxygenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.975 |
PA4121 | hpcC | PA4121 | PA4123 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the aldehyde dehydrogenase family. | 0.994 |
PA4121 | hpcD | PA4121 | PA4125 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 5-carboxymethyl-2-hydroxymuconate isomerase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.998 |
PA4121 | hpcG | PA4121 | PA4127 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 2-oxo-hept-3-ene-1,7-dioate hydratase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.993 |
PA4122 | PA4120 | PA4122 | PA4120 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.933 |
PA4122 | PA4121 | PA4122 | PA4121 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.997 |