node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA3415 | PA4150 | PA3415 | PA4150 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.933 |
PA3415 | PA4152 | PA3415 | PA4152 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.981 |
PA3415 | aceF | PA3415 | PA5016 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.924 |
PA3415 | acoB | PA3415 | PA4151 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Acetoin catabolism protein AcoB; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.952 |
PA3415 | bkdA1 | PA3415 | PA2247 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 2-oxoisovalerate dehydrogenase (alpha subunit); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity); Belongs to the BCKDHA family. | 0.964 |
PA3415 | pdhA | PA3415 | PA3417 | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.999 |
PA4149 | PA4150 | PA4149 | PA4150 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.962 |
PA4149 | PA4152 | PA4149 | PA4152 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.949 |
PA4149 | PA4153 | PA4149 | PA4153 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 2,3-butanediol dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.792 |
PA4149 | acoB | PA4149 | PA4151 | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Acetoin catabolism protein AcoB; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.928 |
PA4150 | PA3415 | PA4150 | PA3415 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.933 |
PA4150 | PA4149 | PA4150 | PA4149 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.962 |
PA4150 | PA4152 | PA4150 | PA4152 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.995 |
PA4150 | PA4153 | PA4150 | PA4153 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 2,3-butanediol dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.989 |
PA4150 | aceF | PA4150 | PA5016 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.854 |
PA4150 | acoB | PA4150 | PA4151 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Acetoin catabolism protein AcoB; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.999 |
PA4150 | bkdB | PA4150 | PA2249 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Branched-chain alpha-keto acid dehydrogenase (lipoamide component); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.931 |
PA4150 | sucB | PA4150 | PA1586 | Probable dehydrogenase E1 component; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Dihydrolipoamide succinyltransferase (E2 subunit); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.922 |
PA4152 | PA3415 | PA4152 | PA3415 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable dihydrolipoamide acetyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.981 |
PA4152 | PA4149 | PA4152 | PA4149 | Probable hydrolase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.949 |