STRINGSTRING
mexG mexG mexH mexH mexI mexI opmD opmD PA2274 PA2274 PA2697 PA2697 PA4014 PA4014 soxR soxR bauB bauB PA2699 PA2699 pqsE pqsE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mexGHypothetical protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (148 aa)    
Predicted Functional Partners:
mexH
Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.997
mexI
Probable Resistance-Nodulation-Cell Division (RND) efflux transporter; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
  
 0.995
opmD
Probable outer membrane protein precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.995
PA2274
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
  
 0.928
PA2697
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
     0.730
PA4014
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.700
soxR
SoxR; Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron- sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster is employed in vivo to modulate the transcriptional activity of SoxR in response to specific types of oxidative stress (By similarity).
  
  
 0.616
bauB
Hypothetical protein; Involved in the degradation of beta-alanine.
  
     0.522
PA2699
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
    0.510
pqsE
Quinolone signal response protein; Required for the biosynthesis of the quorum-sensing signaling molecules 2-heptyl-4(1H)-quinolone (HHQ) and 2-heptyl-3-hydroxy-4(1H)- quinolone (Pseudomonas quinolone signal or PQS), which are important for biofilm formation and virulence. Catalyzes the hydrolysis of the intermediate 2-aminobenzoylacetyl-CoA (2-ABA-CoA) to form 2- aminobenzoylacetate (2-ABA), the precursor of HHQ. In vitro, can also hydrolyze other substrates such as S-ethyl-acetothioacetate and acetoacetyl-CoA, but is inactive against anthraniloyl-CoA, malonyl-CoA and octanoyl-CoA. Be [...]
     
 0.497
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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