node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA5271 | rlmG | PA5271 | PA4617 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.655 |
cmoB | rlmG | PA0774 | PA4617 | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.510 |
cmoB | rlmH | PA0774 | PA4004 | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.639 |
cmoB | rlmJ | PA0774 | PA5019 | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | Conserved hypothetical protein; Specifically methylates the adenine in position 2030 of 23S rRNA. | 0.417 |
cmoB | rlmL | PA0774 | PA3048 | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.481 |
cmoB | trmD | PA0774 | PA3743 | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.634 |
cmoB | truD | PA0774 | PA3626 | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.640 |
obg | rlmG | PA4566 | PA4617 | GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.533 |
obg | trmD | PA4566 | PA3743 | GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.789 |
rlmG | PA5271 | PA4617 | PA5271 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.655 |
rlmG | cmoB | PA4617 | PA0774 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | 0.510 |
rlmG | obg | PA4617 | PA4566 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | GTP-binding protein Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.533 |
rlmG | rlmH | PA4617 | PA4004 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.556 |
rlmG | rlmJ | PA4617 | PA5019 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Conserved hypothetical protein; Specifically methylates the adenine in position 2030 of 23S rRNA. | 0.594 |
rlmG | rlmL | PA4617 | PA3048 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.914 |
rlmG | rsuA | PA4617 | PA0733 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Probable pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.597 |
rlmG | trmD | PA4617 | PA3743 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.493 |
rlmG | truD | PA4617 | PA3626 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.641 |
rlmG | tsaC | PA4617 | PA0022 | Conserved hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. | 0.572 |
rlmH | cmoB | PA4004 | PA0774 | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | 0.639 |