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PA4675 PA4675 fpvB fpvB icmP icmP vreA vreA tonB1 tonB1 PA1363 PA1363 fpvA fpvA fptA fptA PA3688 PA3688 foxA foxA PA3268 PA3268
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA4675Probable TonB-dependent receptor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (742 aa)    
Predicted Functional Partners:
fpvB
Second ferric pyoverdine receptor FpvB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
  
 0.820
icmP
Insulin-cleaving metalloproteinase outer membrane protein precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.732
vreA
VreA; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
  
 
 0.713
tonB1
TonB1; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
 
 
 0.699
PA1363
Probable sigma-70 factor, ECF subfamily; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the sigma-70 factor family. ECF subfamily.
   
  
 0.663
fpvA
Ferripyoverdine receptor; Receptor for the siderophore ferripyoverdine.
 
  
 0.642
fptA
Fe(III)-pyochelin outer membrane receptor precursor; High-affinity outer membrane receptor required for the transport of Fe(3+)-pyochelin.
 
  
 0.631
PA3688
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
   
 0.627
foxA
Ferrioxamine receptor FoxA; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.606
PA3268
Probable TonB-dependent receptor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.598
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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