STRINGSTRING
hitA hitA hitB hitB PA5216 PA5216 PA3538 PA3538 PA5217 PA5217 PA3526 PA3526 PA1069 PA1069 PA5340 PA5340 PA1043 PA1043 icmP icmP tonB1 tonB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hitAFerric iron-binding periplasmic protein HitA; Product name confidence: Class 2 (High similarity to functionally studied protein). (335 aa)    
Predicted Functional Partners:
hitB
Iron (III)-transport system permease HitB; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.999
PA5216
Probable permease of ABC iron transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.979
PA3538
Probable ATP-binding component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the ABC transporter superfamily.
 
 
 0.960
PA5217
Probable binding protein component of ABC iron transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the bacterial solute-binding protein 1 family.
  
 
0.948
PA3526
Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
    
 
 0.713
PA1069
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.700
PA5340
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
  
 0.699
PA1043
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.697
icmP
Insulin-cleaving metalloproteinase outer membrane protein precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
    0.670
tonB1
TonB1; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity).
  
  
 0.581
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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