STRINGSTRING
PA4709 PA4709 phuT phuT hmuV hmuV PA4707 PA4707 phuR phuR PA4705 PA4705 PA2033 PA2033 pvdO pvdO pchR pchR PA5093 PA5093 foxR foxR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA4709Probable hemin degrading factor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). (354 aa)    
Predicted Functional Partners:
phuT
Heme-transport protein, PhuT; Class 2: Function of highly similar gene experimentally demonstrated in another organism (and gene context consistent in terms of pathways its involved in (if known).
 
  
 0.999
hmuV
Probable ATP-binding component of ABC transporter; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
  
 0.987
PA4707
Probable permease of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
  
 0.968
phuR
Heme/hemoglobin uptake outer membrane receptor PhuR precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
  
 0.954
PA4705
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
    0.780
PA2033
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.746
pvdO
PvdO; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.726
pchR
Transcriptional regulator PchR; Positive activator of the genes for pyochelin and ferripyochelin receptors.
   
    0.718
PA5093
Probable histidine/phenylalanine ammonia-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
      
 0.710
foxR
Anti-sigma factor FoxR; Class 1: Function experimentally demonstrated in P. aeruginosa.
   
  
 0.680
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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