node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0583 | folB | PA0583 | PA0582 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.998 |
PA0583 | folC | PA0583 | PA3111 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Folylpolyglutamate synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the folylpolyglutamate synthase family. | 0.598 |
PA0583 | folE1 | PA0583 | PA3438 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.766 |
PA0583 | folE2 | PA0583 | PA1674 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.767 |
PA0583 | folK | PA0583 | PA4728 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the HPPK family. | 0.927 |
PA0583 | folP | PA0583 | PA4750 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.991 |
PA0583 | folX | PA0583 | PA3439 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | D-erythro-7,8-dihydroneopterin triphosphate epimerase; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.797 |
PA0583 | ribD | PA0583 | PA4056 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.704 |
PA0583 | ribE | PA0583 | PA4053 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.477 |
folB | PA0583 | PA0582 | PA0583 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.998 |
folB | folC | PA0582 | PA3111 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Folylpolyglutamate synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the folylpolyglutamate synthase family. | 0.917 |
folB | folE1 | PA0582 | PA3438 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.942 |
folB | folE2 | PA0582 | PA1674 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.758 |
folB | folK | PA0582 | PA4728 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the HPPK family. | 0.997 |
folB | folP | PA0582 | PA4750 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
folB | ribD | PA0582 | PA4056 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.784 |
folB | ribE | PA0582 | PA4053 | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.481 |
folC | PA0583 | PA3111 | PA0583 | Folylpolyglutamate synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the folylpolyglutamate synthase family. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.598 |
folC | folB | PA3111 | PA0582 | Folylpolyglutamate synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.917 |
folC | folE1 | PA3111 | PA3438 | Folylpolyglutamate synthetase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I precursor; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.535 |