node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA3559 | PA4775 | PA3559 | PA4775 | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.869 |
PA3559 | arnB | PA3559 | PA3552 | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | ArnB; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. | 0.995 |
PA3559 | pmrA | PA3559 | PA4776 | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.782 |
PA3559 | pmrB | PA3559 | PA4777 | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | PmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.927 |
PA3559 | speE2 | PA3559 | PA4774 | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.927 |
PA3559 | speH | PA3559 | PA4773 | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.764 |
PA4775 | PA3559 | PA4775 | PA3559 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.869 |
PA4775 | arnB | PA4775 | PA3552 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | ArnB; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. | 0.896 |
PA4775 | pmrA | PA4775 | PA4776 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | PmrA: two-component regulator system response regulator PmrA; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.988 |
PA4775 | pmrB | PA4775 | PA4777 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | PmrB: two-component regulator system signal sensor kinase PmrB; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.985 |
PA4775 | speD | PA4775 | PA0654 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.691 |
PA4775 | speE | PA4775 | PA1687 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.493 |
PA4775 | speE2 | PA4775 | PA4774 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.997 |
PA4775 | speH | PA4775 | PA4773 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.954 |
aguB | speC | PA0293 | PA4519 | N-carbamoylputrescine amidohydrolase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Ornithine decarboxylase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa); Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.988 |
aguB | speD | PA0293 | PA0654 | N-carbamoylputrescine amidohydrolase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. | 0.691 |
aguB | speE | PA0293 | PA1687 | N-carbamoylputrescine amidohydrolase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.980 |
aguB | speE2 | PA0293 | PA4774 | N-carbamoylputrescine amidohydrolase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. | 0.980 |
aguB | speH | PA0293 | PA4773 | N-carbamoylputrescine amidohydrolase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.749 |
arnB | PA3559 | PA3552 | PA3559 | ArnB; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. | Probable nucleotide sugar dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.995 |