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fdhE fdhE fdnH fdnH fdnI fdnI selB selB selA selA fdnG fdnG fdhD fdhD selD selD PA3867 PA3867 PA0487 PA0487 PA2414 PA2414
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fdhEFdhE protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa)    
Predicted Functional Partners:
fdnH
Nitrate-inducible formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
 
  
 0.983
fdnI
Nitrate-inducible formate dehydrogenase, gamma subunit; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.975
selB
Selenocysteine-specific elongation factor; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
  
 0.963
selA
L-seryl-tRNA(ser) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.955
fdnG
Formate dehydrogenase-O, major subunit; Product name confidence: Class 2: Function of highly similar gene experimentally demonstrated in another organism (and gene context consistent in terms of pathways its involved in, if known).
 
  
 0.945
fdhD
Conserved hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.845
selD
Selenophosphate synthetase; Synthesizes selenophosphate from selenide and ATP.
 
   
 0.832
PA3867
Probable DNA invertase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
      
 0.695
PA0487
Probable molybdenum transport regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
   
 0.618
PA2414
L-sorbosone dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein).
      
 0.587
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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