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fdnH fdnH fdnI fdnI fdnG fdnG fdhE fdhE napA napA PA5181 PA5181 fdhA fdhA hutG hutG purU2 purU2 kynB kynB PA3628 PA3628
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fdnHNitrate-inducible formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (309 aa)    
Predicted Functional Partners:
fdnI
Nitrate-inducible formate dehydrogenase, gamma subunit; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 0.999
fdnG
Formate dehydrogenase-O, major subunit; Product name confidence: Class 2: Function of highly similar gene experimentally demonstrated in another organism (and gene context consistent in terms of pathways its involved in, if known).
 
 
 0.999
fdhE
FdhE protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
  
 0.983
napA
Periplasmic nitrate reductase protein NapA; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
 
 0.937
PA5181
Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.911
fdhA
Glutathione-independent formaldehyde dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formaldehyde and acetoaldehyde; Belongs to the zinc-containing alcohol dehydrogenase family.
   
 
 0.903
hutG
N-formylglutamate amidohydrolase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
  0.902
purU2
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
   
 
  0.901
kynB
Kynurenine formamidase, KynB; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation; Belongs to the Cyclase 1 superfamily. KynB family.
     
  0.900
PA3628
Probable esterase; Serine hydrolase involved in the detoxification of formaldehyde.
   
 
  0.900
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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