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ctpL ctpL wspE wspE chpA chpA PA1458 PA1458 PA0178 PA0178 PA1464 PA1464 cheR1 cheR1 PA0177 PA0177 wspC wspC cheB1 cheB1 cheR2 cheR2
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
ctpLProbable chemotaxis transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Chemoreceptor for inorganic phosphate, which is required for taxis at low concentrations of phosphate. Is also responsible for the positive chemotaxis toward 4-chloroaniline (4CA) and catechol. Does not recognize inorganic phosphate directly, but via a complex between the periplasmic protei [...] (657 aa)    
Predicted Functional Partners:
wspE
Probable chemotaxis sensor/effector fusion protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.932
chpA
Component of chemotactic signal transduction system; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.896
PA1458
Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.891
PA0178
Probable two-component sensor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.890
PA1464
Probable purine-binding chemotaxis protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.878
cheR1
Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 
 0.876
PA0177
Probable purine-binding chemotaxis protein; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.838
wspC
Probable protein methyltransferase; Involved in biofilm formation.
 
 
 0.827
cheB1
Probable methyltransferase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
 
 
 0.819
cheR2
Probable chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 
 0.817
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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