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PA4872 PA4872 PA5046 PA5046 maeA maeA gltA gltA lldD lldD lldA lldA mqoB mqoB pykA pykA pykF pykF mqoA mqoA ppc ppc
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PA4872Hypothetical protein; Catalyzes the decarboxylation of oxaloacetate into pyruvate with high efficiency. Is also able to decarboxylate 3- methyloxaloacetate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate. Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family. (287 aa)    
Predicted Functional Partners:
PA5046
Malic enzyme; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.946
maeA
Probable malic enzyme; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the malic enzymes family.
  
 
 0.936
gltA
Citrate synthase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
 
 0.934
lldD
L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
   
 
 0.931
lldA
L-lactate dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein).
   
 
 0.930
mqoB
Malate:quinone oxidoreductase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
 
 0.923
pykA
Pyruvate kinase II; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the pyruvate kinase family.
   
 
 0.922
pykF
Pyruvate kinase I; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the pyruvate kinase family.
   
 
 0.921
mqoA
Malate:quinone oxidoreductase; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.921
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
    
 0.921
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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