node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0400 | PA4130 | PA0400 | PA4130 | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.788 |
PA0400 | PA4513 | PA0400 | PA4513 | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.585 |
PA0400 | cysH | PA0400 | PA1756 | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 3'-phosphoadenosine-5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily. | 0.632 |
PA0400 | cysI | PA0400 | PA1838 | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Sulfite reductase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.846 |
PA0400 | rhdA | PA0400 | PA4956 | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Thiosulfate:cyanide sulfurtransferase; Catalyzes the sulfur transfer reaction from thiosulfate to cyanide, thus converting cyanide to the less toxic thiocyanate. Contributes to P.aeruginosa survival under cyanogenic conditions, and thus provides the bacterium with a defense mechanism against endogenous cyanide toxicity. Is the main cytoplasmic rhodanese in P.aeruginosa, accounting for 90% of total rhodanese activity. | 0.958 |
PA0400 | sseA | PA0400 | PA1292 | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable 3-mercaptopyruvate sulfurtransferase; Transfers a sulfur ion to cyanide or to other thiol compounds. | 0.990 |
PA2062 | rhdA | PA2062 | PA4956 | Probable pyridoxal-phosphate dependent enzyme; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Thiosulfate:cyanide sulfurtransferase; Catalyzes the sulfur transfer reaction from thiosulfate to cyanide, thus converting cyanide to the less toxic thiocyanate. Contributes to P.aeruginosa survival under cyanogenic conditions, and thus provides the bacterium with a defense mechanism against endogenous cyanide toxicity. Is the main cytoplasmic rhodanese in P.aeruginosa, accounting for 90% of total rhodanese activity. | 0.916 |
PA2062 | sseA | PA2062 | PA1292 | Probable pyridoxal-phosphate dependent enzyme; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable 3-mercaptopyruvate sulfurtransferase; Transfers a sulfur ion to cyanide or to other thiol compounds. | 0.917 |
PA4130 | PA0400 | PA4130 | PA0400 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.788 |
PA4130 | PA4513 | PA4130 | PA4513 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.997 |
PA4130 | cysH | PA4130 | PA1756 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 3'-phosphoadenosine-5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily. | 0.993 |
PA4130 | cysI | PA4130 | PA1838 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfite reductase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.902 |
PA4130 | glpE | PA4130 | PA0589 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Conserved hypothetical protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. | 0.914 |
PA4130 | rhdA | PA4130 | PA4956 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Thiosulfate:cyanide sulfurtransferase; Catalyzes the sulfur transfer reaction from thiosulfate to cyanide, thus converting cyanide to the less toxic thiocyanate. Contributes to P.aeruginosa survival under cyanogenic conditions, and thus provides the bacterium with a defense mechanism against endogenous cyanide toxicity. Is the main cytoplasmic rhodanese in P.aeruginosa, accounting for 90% of total rhodanese activity. | 0.979 |
PA4130 | sseA | PA4130 | PA1292 | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Probable 3-mercaptopyruvate sulfurtransferase; Transfers a sulfur ion to cyanide or to other thiol compounds. | 0.972 |
PA4513 | PA0400 | PA4513 | PA0400 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.585 |
PA4513 | PA4130 | PA4513 | PA4130 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.997 |
PA4513 | cysH | PA4513 | PA1756 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 3'-phosphoadenosine-5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily. | 0.973 |
PA4513 | cysI | PA4513 | PA1838 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Sulfite reductase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.990 |
PA4513 | glpE | PA4513 | PA0589 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Conserved hypothetical protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. | 0.911 |