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rhdA rhdA glpE glpE PA4130 PA4130 PA4513 PA4513 PA0400 PA0400 PA4955 PA4955 psd psd cysI cysI sseA sseA cysH cysH PA2062 PA2062
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
rhdAThiosulfate:cyanide sulfurtransferase; Catalyzes the sulfur transfer reaction from thiosulfate to cyanide, thus converting cyanide to the less toxic thiocyanate. Contributes to P.aeruginosa survival under cyanogenic conditions, and thus provides the bacterium with a defense mechanism against endogenous cyanide toxicity. Is the main cytoplasmic rhodanese in P.aeruginosa, accounting for 90% of total rhodanese activity. (271 aa)    
Predicted Functional Partners:
glpE
Conserved hypothetical protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
   
 0.989
PA4130
Probable sulfite or nitrite reductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.979
PA4513
Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
    
 0.959
PA0400
Probable cystathionine gamma-lyase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
 
 
 0.958
PA4955
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
     
 0.954
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
  
  
 0.949
cysI
Sulfite reductase; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.931
sseA
Probable 3-mercaptopyruvate sulfurtransferase; Transfers a sulfur ion to cyanide or to other thiol compounds.
  
 
0.928
cysH
3'-phosphoadenosine-5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily.
    
 0.918
PA2062
Probable pyridoxal-phosphate dependent enzyme; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
 0.916
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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