Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PA1217 | PA2035 | PA1217 | PA2035 | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | 0.949 |
| PA1217 | aruI | PA1217 | PA4977 | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-ketoarginine decarboxylase, AruI; Catalyzes the decarboxylation of 2-ketoarginine, leading to the formation of 4-guanidinobutyraldehyde. | 0.781 |
| PA1217 | ilvC | PA1217 | PA4694 | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.906 |
| PA1217 | ilvD | PA1217 | PA0353 | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | Dihydroxy-acid dehydratase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the IlvD/Edd family. | 0.987 |
| PA1217 | ilvH | PA1217 | PA4695 | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase isozyme III small subunit; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.947 |
| PA1217 | leuB | PA1217 | PA3118 | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.943 |
| PA1217 | mdlC | PA1217 | PA4901 | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | Benzoylformate decarboxylase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the TPP enzyme family. | 0.733 |
| PA2035 | PA1217 | PA2035 | PA1217 | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | Probable 2-isopropylmalate synthase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.949 |
| PA2035 | aruI | PA2035 | PA4977 | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | 2-ketoarginine decarboxylase, AruI; Catalyzes the decarboxylation of 2-ketoarginine, leading to the formation of 4-guanidinobutyraldehyde. | 0.724 |
| PA2035 | ilvC | PA2035 | PA4694 | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.982 |
| PA2035 | ilvD | PA2035 | PA0353 | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | Dihydroxy-acid dehydratase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the IlvD/Edd family. | 0.848 |
| PA2035 | ilvH | PA2035 | PA4695 | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | Acetolactate synthase isozyme III small subunit; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.957 |
| PA2035 | leuB | PA2035 | PA3118 | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.977 |
| PA2035 | mdlC | PA2035 | PA4901 | Probable decarboxylase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the TPP enzyme family. | Benzoylformate decarboxylase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the TPP enzyme family. | 0.740 |
| PA4978 | aruH | PA4978 | PA4976 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Arginine:Pyruvate Transaminase, AruH; Catalyzes the conversion of L-arginine into 2-ketoarginine via transamination. L-arginine is the best substrate, but it can also use L-lysine, L-methionine, L-leucine, ornithine and L-glutamine, which indicates that it may have a broader physiological function in amino acid catabolism. | 0.711 |
| PA4978 | aruI | PA4978 | PA4977 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 2-ketoarginine decarboxylase, AruI; Catalyzes the decarboxylation of 2-ketoarginine, leading to the formation of 4-guanidinobutyraldehyde. | 0.786 |
| PA5312 | aruH | PA5312 | PA4976 | Probable aldehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aldehyde dehydrogenase family. | Arginine:Pyruvate Transaminase, AruH; Catalyzes the conversion of L-arginine into 2-ketoarginine via transamination. L-arginine is the best substrate, but it can also use L-lysine, L-methionine, L-leucine, ornithine and L-glutamine, which indicates that it may have a broader physiological function in amino acid catabolism. | 0.496 |
| PA5312 | aruI | PA5312 | PA4977 | Probable aldehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aldehyde dehydrogenase family. | 2-ketoarginine decarboxylase, AruI; Catalyzes the decarboxylation of 2-ketoarginine, leading to the formation of 4-guanidinobutyraldehyde. | 0.971 |
| PA5312 | mdlC | PA5312 | PA4901 | Probable aldehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aldehyde dehydrogenase family. | Benzoylformate decarboxylase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the TPP enzyme family. | 0.722 |
| aruH | PA4978 | PA4976 | PA4978 | Arginine:Pyruvate Transaminase, AruH; Catalyzes the conversion of L-arginine into 2-ketoarginine via transamination. L-arginine is the best substrate, but it can also use L-lysine, L-methionine, L-leucine, ornithine and L-glutamine, which indicates that it may have a broader physiological function in amino acid catabolism. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.711 |
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