waaC protein (Pseudomonas aeruginosa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

waaC

Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). (355 aa)

Predicted Functional Partners:

waaP

0.999

waaG

0.999

waaF

0.998

waaA

0.996

rfaE

0.983

PA5006

0.981

PA5007

0.958

gmhA

0.944

PA5008

0.939

gmhB

0.900

Your Current Organism:

Pseudomonas aeruginosa

NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PA5006	PA5007	PA5006	PA5007	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.994
PA5006	PA5008	PA5006	PA5008	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.993
PA5006	rfaE	PA5006	PA4996	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	LPS biosynthesis protein RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family.	0.519
PA5006	waaC	PA5006	PA5011	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.981
PA5006	waaF	PA5006	PA5012	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Heptosyltransferase II; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.972
PA5006	waaG	PA5006	PA5010	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase WaaG; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.984
PA5006	waaP	PA5006	PA5009	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Lipopolysaccharide kinase WaaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core. The phosphorylation of the lipopolysaccharide core seems to occur prior to translocation to the periplasm and attachment of O-antigen. Also has protein-tyrosine kinase activity: autophosphorylates on all Tyr residues; in vitro can phosphorylate poly(Glu,Tyr).	0.997
PA5007	PA5006	PA5007	PA5006	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.994
PA5007	PA5008	PA5007	PA5008	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.998
PA5007	waaC	PA5007	PA5011	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.958
PA5007	waaF	PA5007	PA5012	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Heptosyltransferase II; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.969
PA5007	waaG	PA5007	PA5010	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase WaaG; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.990
PA5007	waaP	PA5007	PA5009	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Lipopolysaccharide kinase WaaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core. The phosphorylation of the lipopolysaccharide core seems to occur prior to translocation to the periplasm and attachment of O-antigen. Also has protein-tyrosine kinase activity: autophosphorylates on all Tyr residues; in vitro can phosphorylate poly(Glu,Tyr).	0.993
PA5008	PA5006	PA5008	PA5006	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.993
PA5008	PA5007	PA5008	PA5007	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	0.998
PA5008	waaC	PA5008	PA5011	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.939
PA5008	waaF	PA5008	PA5012	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Heptosyltransferase II; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).	0.955
PA5008	waaG	PA5008	PA5010	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase WaaG; Product name confidence: Class 2 (High similarity to functionally studied protein).	0.991
PA5008	waaP	PA5008	PA5009	Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).	Lipopolysaccharide kinase WaaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core. The phosphorylation of the lipopolysaccharide core seems to occur prior to translocation to the periplasm and attachment of O-antigen. Also has protein-tyrosine kinase activity: autophosphorylates on all Tyr residues; in vitro can phosphorylate poly(Glu,Tyr).	0.966
gmhA	gmhB	PA4425	PA0006	Sedoheptulose 7-phosphate isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.	Conserved hypothetical protein; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position; Belongs to the GmhB family.	0.999